I actually enjoy hearing a bit of keyboard/mouse noise in videos of people demonstrating things or playing games. Obviously it shouldn't be overpowering but it gives it that little bit of authenticity and "human" feel whereas if you have a super aggressive audio filter it just sounds kinda dead and with no soul.
It's obviously still on you to make sure that it's not too loud and that you can still be understood clearly, but that goes with any kind of audio.
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